News Worms
News Worms

Poor sleep may point to onset of Alzheimers disease

Poor sleep may point to onset of Alzheimers disease

Research from earlier this year may have revealed another clue in Alzheimer's early start; it found that signs of brain plaque buildup can be seen in patients as early as 10 years before they begin to experience disease symptoms.

While some of these relationships were strong when looking at everyone as a group, not everyone with sleep problems has abnormalities in their spinal fluid.

People who sleep badly could be at a greater risk of Alzheimer's later in life, new research has suggested.

Amyloid plaques develop in parts of the brain that play a role in visual recognition and memory, causing symptoms of the disorder.

Scientists have come up with the most detailed images ever of the tau protein that aggregates in the brain of patients with Alzheimer's disease, leading to the death of brain cells.

We won't know the full ramifications of this discovery until scientists have a chance to follow up on the new findings presented here, but it's clear that this could be a major turning point in studying how to counter these harmful protein clumps, with Ghetti describing the result as one of the major discoveries of the last quarter century of Alzheimer's research.

A journal for the American Academy of Neurology published a study that is trying to figure out the connection between the quality of sleep and protein levels that are tied to dementia development.

Researchers found that those who had more sleep problems, including worse self-reported sleep quality and daytime sleepiness, had consistently lower levels of cerebrospinal fluid.

Professor Dr Barbara Bendlin, from the University of Wisconsin-Madison, said: 'Previous evidence has shown that sleep may influence the development or progression of Alzheimer's disease in various ways. Dr. Bendlin explained that the study not only looked for amyloid but also biological markers in the participants' spinal fluid.

"The ability to picture what the lock looks like could help scientists design more precise drugs that act on the tau protein and stop damage to the brain". "In the deepest stage of sleep, the brain cleans itself out of plaque and other toxic materials that trigger Alzheimer's disease".

Fellow senior author Dr Michel Goedert, who also worked on the original research 30 years ago, said: "We have known for nearly three decades that the abnormal assembly of Tau protein into filaments is a defining characteristic of Alzheimer's disease".

She added that doctors should encourage adults to improve the quality of their sleep to reduce the number of Alzheimer's sufferers in the future. As the mice slept, their brains actually changed shape, expanding to allow them to better flush out these toxins that had built up during the day, The Huffington Post reported.

'It may be possible that early intervention for people at risk of Alzheimer's disease may prevent or delay the onset of the disease'.

For example, there was no association seen between people who had sleep apnea and markers for Alzheimer's in their spinal fluid.


editors' picks

July 07, 2017
Wimbledon ladies star screams 'F***, HELP ME, HELP ME' after horror injury
Bethanie Mattek-Sands has been rushed off to hospital, from playing a match at Wimbedon, after a horrific fall on court 17. Mattek-Sands's husband Justin tried to console his wife as medics arrived, while Cirstea was distraught and in tears.

July 07, 2017
Getting to Work on Health Care
But they do reveal a lot about how the two parties understand health care ― and the policy tradeoffs each is willing to make. I remember what it was like before the Affordable Care Act - many patients came in our doors without health insurance.

July 07, 2017
A Newly Discovered Photograph Might Prove That Amelia Earhart Survived Her Flight
The History Channel investigative team found the photograph amongst a series of declassified information. The documentary, " Amelia Earhart: The Lost Evidence ", premiers Sunday night on The History Channel .

July 07, 2017
Japan trade deal welcomed by European wine and dairy sectors
A trade deal between the two sides, with a combined market of 637 million, would cover about 28 percent of the world's economy. One condition for the immediate removal of wine tariffs was that Europe would accept Japanese production methods.

July 07, 2017
China says it could issue travel alert for India
Amid an ongoing standoff, China has warned India to withdraw its troops before any dialogue can be initiated. But the Himalayan kingdom of Bhutan has remained firmly within New Delhi's sphere of influence.

July 07, 2017
Most Anticipated Nintendo Games Still to Come in 2017
You can play this mode as a Ranked Battle and if you have the skills you will be awarded with a medal within the game. Nintendo's new app, called Nintendo Switch Online , acts as a central hub for all app-compatible games.

July 07, 2017
China ties affected by some negative factors: Xi Jinping
A White House statement , however, said Trump discussed the growing threat of North Korea's nuclear and missile programs with Xi. The United States and South Korea responded with an exercise of their own, firing missiles off of South Korea's eastern coast.

July 07, 2017
NYPD officer killed in Bronx: Gunman's girlfriend called 911 hours earlier
Officers chased the assailant on foot for a block before he drew a revolver and they shot and killed him, the department said. The 12-year NYPD veteran also had medical vocational training, including certification as a phlebotomist, police said.

July 06, 2017
More Than 100 People Shot In Chicago Over Holiday Weekend; 15 Killed
At the weekend, Chicago police said shootings this year had declined 14% compared with the first six months of last year. At least 101 were reported wounded between Friday and Wednesday morning, mostly toward the city's south and west sides.

July 06, 2017
NYPD Officer Assassinated In Police Vehicle
Officers opened fire and killed Bonds, accidentally striking a bystander, who is now in "stable condition", in the process. Her partner radioed for help and a sergeant and uniformed officer confronted the suspect around a block from the shooting.