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News Worms


Scientists develop new regenerative tissue technology

Scientists develop new regenerative tissue technology

The technology called Tissue Nanotransfection (TNT) is still in its experimental phase but it holds promise in saving the lives of vehicle crash victims and deployed soldiers who get injured on site.

"We have shown that the skin is a fertile land where we can grow the elements of any organ that is declining", Sen said, Science Daily reported.

A small electric current fires DNA into skin cells to convert them into natural cell building blocks which helps to fix the damaged areas such as arteries and even organs like the heart.

The device is a tiny silicone chip about the size of a dime that "injects genetic code into skin cells, turning those skin cells into other types of cells required for treating diseased conditions", states a release from the university.

In a series of lab tests, explains Sen on the university website, researchers applied the chip to the injured legs of mice that vascular scans showed had little to no blood flow.

It takes just a fraction of a second.

A device developed at The Ohio State University can heal damaged organs by causing existing skin cells to develop into vascular cells. Within one week, active blood vessels appeared in the injured leg, and by the second week, the leg was saved. The findings were published August 7 in Nature nanotechnology.

The team were also able to use the device to convert skin cells on mice, into nerve cells which were then injected into the brains of mice who had experienced a stroke, helping them to recover.

According to the researchers, the technology successfully worked 98 percent of the time.

The breakthrough technology marks the first time that cells have been reprogrammed in a live body.

TNT technology has two major components: First is a nanotechnology-based chip created to deliver cargo to adult cells in the live body.

Because it is the body's own cells that are being converted, the immune system does not attack them and so there is no need for immunosuppressant drugs.

Researchers said the technology itself is small and portable, allowing it to be used outside of a doctor's office or lab.

"The concept is very simple", says L. James Lee, a professor of chemical and biomolecular engineering with Ohio State's College of Engineering. "So this is the beginning, more to come".

Dr. Sen said he hopes to begin trials within a year. Let us know in the comment section below!

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